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Lyophilizied human serum-based matrix containing multi-parameter analytes for HumaCLIA SR assays To be used with : TSH, fT3, fT4, T3, T4, anti-TG, anti-TPO, TG, AFP, CEA,CA-125, CA 19-9,CA 15-3, FSH, LH, HCG, Progesterone, Testosterone, Prolactin, Estradiol (E2), DHEA-S, PSA*, fPSA*, 25-OH Vitamin D, PTH, Folate, Vitamin B12, Cortisol, Troponin I, CK-MB, Myoglobin *No CE – only for use outside Europe
Pancreatic amylase activity measurements in serum and urine are mainly applied for the diagnosis of pancreatic disorders as well as for detecting the development of complications. As pancreatic and salivary amylase show a structural homology of 97%, the only method to distinguish is to use an assay based on monoclonal antibodies to inhibit the salivary enzyme. The amylase in the blood is eliminated through the kidneys and excreted into the urine, therefore, elevated serum activity is reflected in the rise of urinary amylase activity. For confirmation of an acute pancreatitis an additional measurement of lipase is recommended. Enzymatic colorimetric test for the quantitative determination of pancreatic amylase in human serum, plasma and urine.
Quantitative determination of IgG / IgA / IgM antibodies to phosphatidylethanolamine. Calibration: 6.25 / 12.5 / 25 / 50 / 100 U/ml Cut-off: 15 U/ml
Determination of antibodies to phosphatidylserine
Quantitative determination of IgG / IgM antibodies to phospholipids. Calibration: 6 / 12.5 / 25 / 50 / 100 U/ml Cut-off: 15-25 U/ml
Inorganic phosphorus (PHOS, PO3) is measured for diagnosis and therapy control of various disorders such as bone diseases, chronic kidney disease, dialysis patients, kidney stones, after thyroid surgery, diseases of the parathyroid gland, chronic alcoholism, in intensive care (parenteral nutrition, ventilated patients), suspected Vit D deficiency, muscle weakness and bone pain. UV test for quantitative determination of inorganic phosphate in human serum.
Potassium measurements are used in the diagnosis and treatment of hypokalemia (chronic ingestion of diuretics and laxatives, with/without disorders of the acid-base balance), hyperkalemia (overadministration of potassium, acidosis, or crush injuries), renal failure, Addison`s disease or other diseases involving electrolyte imbalance. Photometric tests for the quantitative determination of potassium in human serum and heparinised plasma.
Quantitative determination of IgG antibodies to proteinase 3. Calibration: 2.5 / 7.4 / 22.2 / 66.7 / 200 U/ml Cut-off: 10 U/ml
Total protein (TP) is a major component of blood and the sum of all circulating proteins. Total protein is measured for diagnosis and therapy control of a variety of diseases involving liver, kidney or bone marrow as well as other metabolic and nutritional disorders. Hypoproteinemia may be caused by abnormal synthesis, protein malnutrition, protein malabsorption, protein loss and after infusions. Hyperproteinemia may be caused by monoclonal gammopathy, severe chronic inflammatory and autoimmune processes. Colorimetric test for the quantitative determination of total protein in human serum and plasma.
Quantitative determination of IgG / IgA / IgM antibodies to prothrombin. Calibration: 6.25 / 12.5 / 25 / 50 / 100 U/ml Cut-off: 30 U/ml
Quantitative determination of IgG antibodies to RA33. Calibration: 12.5 / 25 / 50 / 100 / 200 U/ml Cut-off: 25 U/ml
Quantitative determination of IgM antibodies to rheumatoid factor. Calibration: 12.5 / 25 / 50 / 100 / 200 U/ml Cut-off: 15 IU/ml
Qualitative determination of antibodies to salmonella.
Quantitative / qualitative determination of IgG antibodies to Scl70. Calibration: 12.5/25/50/100/200 U/ml Cut-off: 25 U/ml
Quantitative / qualitative determination of IgG antibodies to SmD. Calibration: 12.5 /25 / 50 / 100 / 200 U/ml Cut-off: 25 U/ml
Sodium measurements are used in the diagnosis and treatment of disturbances of fluid and electrolyte balance, e.g. due to a loss of water or salt, and other serum electrolytes deviating from their reference interval by polyuric-polydypsic syndromes and impaired thirst, renal diseases, hypertension, disorders of the acid-base balance, some endocrine diseases, edema, excessive sodium intake. Colorimetric tests for the quantitative determination of sodium in human serum and heparinized plasma.
Determination of antibodies to ß2-Glycoprotein 1
Quantitative / qualitative determination of IgG antibodies to SS-A/Ro. Calibration: 12.5 / 25 / 50 / 100 / 200 U/ml Cut-off: 25 U/ml
Quantitative / qualitative determination of IgG antibodies to SS-B/La. Calibration: 12.5 / 25 / 50 / 100 / 200 U/ml Cut-off: 25 U/ml
Determination of antibodies to thyroglobulin
Quantitative determination of antibodies to thyroperoxidase.
Quantitative determination of Thyrotropin.
The iron and total iron binding capacity (TIBC) levels are influenced by changes in iron intake, absorption, storage, and release mechanisms. Such changes are indicative of a wide range of dysfunctions including anemias, nephrosis, cirrhosis and hepatitis. Iron and TIBC measurements are interrelated parameters for the diagnosis of the iron status. Saturation and absorbant reagents for sample preparation for the determination of total iron binding capacity (TIBC) in human serum or heparinised plasma.
Transferrin is the principle plasma protein for the transport of iron. Transferrin is a negative acute phase reactant and will decrease during any inflammatory state or malignancy. Increased levels of transferrin are found in iron deficiency, pregnancy, oestrogen administration and lipoidal nephrosis. Decreased levels may be encountered in hereditary deficiencies, testosterone administration, infection, acute inflammation, some forms of nephrosis, tumors, haemochromatosis, acute malaria and malnutrition. Immunoturbidimetric test for the quantitative determination of transferrin in human serum.
The measurement of triglycerides (TG) is used for diagnosis of primary and secondary hyperlipoproteinemias, primary and secondary prevention of coronary vascular disease (CHD), risk marker of metabolic syndrom, LDL-c calculation using the Friedewald formula as well as control of dietary and medical lipid lowering. Enzymatic colorimetric test for the quantitative determination of triglycerides in human serum and plasma.
Quantitative determination of antibodies to tissue transglutaminase.
Quantitative / qualitative determination of IgG antibodies to U1-snRNP. Calibration: 12.5/25/50/100/200 U/ml Cut-off: 25 U/ml
Urea (UREA, BUN) measurements are used in the diagnosis, differential diagnosis, assessment and therapy control of certain renal and metabolic diseases such as acute renal failure, terminal renal disease, and metabolic status of intensive care and dialysis patients. Urea and creatinine determinations are frequently performed together in the differential diagnosis of kidney function. Conversion factor for UREA, BUN [mg/dl] Conc. (UREA) = 2.14 x conc. (BUN); conc. (BUN) = 0.47 x conc. (UREA) Enzymatic colorimetric test and fully enzymatic UV test for the quantitative determination of urea in human serum, plasma and urine.
Uric acid measurements are used in the diagnosis and therapy control of numerous renal and metabolic disorders, including chronic kidney disease, kidney stones, renal failure, gout, hyperlipidemia, leukemia, psoriasis, starvation or other wasting conditions and of patients receiving cytotoxic drugs or cyclosporine therapy in transplant recipients. Enzymatic colorimetric test with or without ascorbate oxidase for the quantitative determination of uric acid in human serum, plasma and urine.
The determination of total protein in urine supports the diagnosis and treatment of primary and secondary kidney disease and the diagnosis of diseases associated with cardiac and thyroid function. Increased total protein concentration in the urine (proteinuria) is a very common urinary finding and is one of the leading symptoms of kidney disease in addition to reduced eGFR. Increased total protein concentrations in cerebrospinal fluid (CSF) are observed in a variety of disease states of the central nervous system (CNS), e.g. cerebral haemorrhage, bacterial or viral meningitis, inflammatory CNS disorders and tumors. Colorimetric test for the quantitative determination of total protein in human urine and cerebrospinal fluid (CSF).

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