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The determination of total protein in urine supports the diagnosis and treatment of primary and secondary kidney disease and the diagnosis of diseases associated with cardiac and thyroid function. Increased total protein concentration in the urine (proteinuria) is a very common urinary finding and is one of the leading symptoms of kidney disease in addition to reduced eGFR. Increased total protein concentrations in cerebrospinal fluid (CSF) are observed in a variety of disease states of the central nervous system (CNS), e.g. cerebral haemorrhage, bacterial or viral meningitis, inflammatory CNS disorders and tumors. Colorimetric test for the quantitative determination of total protein in human urine and cerebrospinal fluid (CSF).

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